Line by Line
Most women with advanced ovarian, tubal or peritoneal cancer take drugs for years, one line of treatment after another. Platinum, PARP inhibitors, bevacizumab, antibody-drug conjugates: what each does, and what the trials show.
Mensagens populares deste blogue
Provas Insanas - Westfield Sydney to Melbourne Ultramarathon 1983
- What’s your secret? - I am just gonna keep running… Cliff Young I will write this post in English. Actually, I will mostly just re-print information from several sources, but I will show all references, in order not to incur in plagiarism. This is the story of an ordinary man who performs extraordinary feats. His name was Cliff Young, and he was the least likely hero that any Nation could come up with. "Albert Ernest Clifford "Cliff" Young , OAM (8 February 1922 [1] – 2 November 2003 [2] ) was an Australian potato farmer [2] and athlete from Beech Forest, Victoria . Born the eldest son and the third of seven children of Mary and Albert Ernest Young on 8 February 1922, Albert Ernest Clifford Young grew up on a farm in Beech Forest in southwestern Victoria. [1] " https://en.wikipedia.org/wiki/Cliff_Young_(athlete) ...
What the Warning Shot Taught Us
What the Warning Shot Taught Us Closing synthesis · technology · October 2026 The incident demonstrated a failure of control with real consequences. The harder question is what follows from that evidence: for the systems we build, the claims we accept, and the things we still need to learn.
When the Score Becomes the Goal
When the Score Becomes the Goal Incentives, people and AI · 8 October 2026 People and AI systems can meet a target while defeating its purpose. The consequences range from wasted effort to irreversible harm. What determines how far the failure travels?
Le Grand Raid des Pyrénées
Como se ultrapassa a adversidade? Onde vamos buscar as forças para persistir quando todas as fibras do nosso corpo nos ordenam que é altura de desistir? Dizem que a fadiga é uma ficção que o cérebro engendra para ordenar ao corpo que é altura de parar, antes que algo irreparável o pare definitivamente. Talvez a realidade seja toda ela uma ficção criada pela nossa mente. Ou então é um enredo que o nosso cérebro constroi, dinâmica e interactivamente, para se conseguir orientar num mundo complexo e desprovido de um propósito independente da nossa vontade. Há investigadores que dizem que temos um cérebro “social” composto por módulos, com diferentes funções. A comandar esses módulos (ou ser comandado por eles) poderá, ou não, existir uma identidade denominada o “eu”, o “self”, a “consciência”, ou o que lhe queiramos chamar. A razão porque construimos percursos e prosseguimos objectivos é porque necessitamos de um ou vários propósitos que nos orientem nesta vida. Como não so...
How Trust Becomes Access
Explainer · technology · October 2026 How Trust Becomes Access A software supply-chain attack can begin with something as ordinary as installing a useful library. This companion to The Load-Bearing Volunteer follows the steps between accepting software and handing it authority — and shows where the chain can break. Reading time ≈ 9 min · Draft · Last updated: 4 October 2026
Grown Not Built
Grown, Not Built The AI series · 8 October 2026 Nobody writes the rules a modern AI model follows. They grow out of training. That makes unintended behaviour something to expect, and it puts the responsibility on the people who choose the conditions it grows in.
Many Ways to Be Clever
Many Ways to Be Clever The AI series · 8 October 2026 The biggest brain on Earth belongs to a whale that is not the cleverest animal. In brains and in AI models alike, what a system can do depends less on its size than on where the capacity goes and what it was built for.
The Company We Keep
In 2016 Ed Yong’s I Contain Multitudes argued that every animal is a crowd. Ten years on, which parts of the microbiome story held up, which were hype, and how much of the hype had the book already warned against?
Mostly Machines
This blog’s counter says 336,000 views. Most of them were not people. What three tools show, why they disagree, how to count better, and my own estimate of how many humans actually read here. Essay · this blog · October 2026
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